How do you explain the absence of aldehyde group in the pentaacetate of d-glucose?
Question: How do you explain the absence of aldehyde group in the pentaacetate of d-glucose?
The absence of aldehyde group in the pentaacetate of D-glucose can be explained by the reaction mechanism that occurs during the acetylation process. Acetylation is a chemical reaction that involves the addition of an acetyl group (-COCH3) to a molecule, often used to protect aldehyde and hydroxyl groups from further reactions. In the case of D-glucose, the acetylation reaction involves the addition of five acetyl groups to the hydroxyl groups of glucose to form pentaacetate. This reaction occurs under acidic conditions and results in the conversion of the aldehyde group of glucose to an acetal group, which is not reactive towards the acetylating agent. Therefore, the absence of the aldehyde group in the pentaacetate of D-glucose is due to its conversion to an acetal group during the acetylation process.
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