Gal80 is mutated such that it cannot interact with gal3. what effect on transcription would you expect to see in the presence of galactose?


Question: Gal80 is mutated such that it cannot interact with gal3. what effect on transcription would you expect to see in the presence of galactose?

Gal80 is a regulatory protein that interacts with Gal3 to control the transcription of genes involved in galactose metabolism. Gal3 is a galactose-binding protein that regulates the activity of Gal80.


In the absence of galactose, Gal3 binds to Gal80, resulting in the repression of genes involved in galactose metabolism. In the presence of galactose, Gal3 releases Gal80, leading to the activation of these genes.


If Gal80 is mutated such that it cannot interact with Gal3, it would not be able to release Gal80 from its repression of genes involved in galactose metabolism, even in the presence of galactose. As a result, the transcription of genes involved in galactose metabolism would be repressed, and the cells would not be able to metabolize galactose efficiently.


Therefore, the mutation in Gal80 would result in a decrease in the transcription of genes involved in galactose metabolism in the presence of galactose.



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